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Opposing roles for distinct LINC complexes in regulation of the small GTPase RhoA

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Different forms of nuclear envelope–spanning LINC complexes have opposing roles in the transcription-independent control of the small GTPase RhoA. Competition between LINC complexes in the nuclear envelope may therefore dictate… Click to show full abstract

Different forms of nuclear envelope–spanning LINC complexes have opposing roles in the transcription-independent control of the small GTPase RhoA. Competition between LINC complexes in the nuclear envelope may therefore dictate the outcome of signaling to cytoskeletal networks.

Keywords: linc complexes; opposing roles; gtpase rhoa; small gtpase; linc

Journal Title: Molecular Biology of the Cell
Year Published: 2017

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