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The polarity regulator Par3 directs the reorganization of the apical membrane in polarized cells through the action of phosphatidylinositol 3-kinase and the Rac1 exchange factor Tiam1. This mechanism may be… Click to show full abstract
The polarity regulator Par3 directs the reorganization of the apical membrane in polarized cells through the action of phosphatidylinositol 3-kinase and the Rac1 exchange factor Tiam1. This mechanism may be exploited by pathogens to bypass the epithelial barrier.
Keywords:
par3 integrates;
apical membrane;
phosphatidylinositol kinase
Journal Title: Molecular Biology of the Cell
Year Published: 2017
Link to full text (if available)
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Journal Title: Molecular Biology of the Cell
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!