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DDB2 is a multifunctional protein that participates in both nucleotide excision repair and regulation of gene transcription. In colon cancer cells, chromatin association of XRCC5/6, in the absence of DNA… Click to show full abstract
DDB2 is a multifunctional protein that participates in both nucleotide excision repair and regulation of gene transcription. In colon cancer cells, chromatin association of XRCC5/6, in the absence of DNA damage, depends on DDB2, and the DDB2–XRCC5/6 interaction promotes the transcription of the antiangiogenic gene SEMA3A.
Keywords:
dna damage;
xrcc5 absence;
absence dna;
association xrcc5;
gene;
chromatin association
Journal Title: Molecular Biology of the Cell
Year Published: 2017
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Journal Title: Molecular Biology of the Cell
Year Published: 2017
Link to full text (if available)
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recommendations!