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Shear stress induces noncanonical autophagy in intestinal epithelial monolayers

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Shear stress applied on the apical side of polarizing intestinal cells induces vacuole formation via the autophagy machinery. This response is relayed through apical microvilli that act as mechanosensors linking… Click to show full abstract

Shear stress applied on the apical side of polarizing intestinal cells induces vacuole formation via the autophagy machinery. This response is relayed through apical microvilli that act as mechanosensors linking the physical environment to the intracellular trafficking pathways.

Keywords: induces noncanonical; intestinal epithelial; autophagy intestinal; shear stress; stress induces; noncanonical autophagy

Journal Title: Molecular Biology of the Cell
Year Published: 2017

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