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Mechanical loading regulates organization of the actin cytoskeleton and column formation in postnatal growth plate

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Longitudinal growth of bones occurs at the growth plates, where chondrocytes align into columns that allow directional growth. Mechanical load and force on chondrocytes regulate the organization of the postnatal… Click to show full abstract

Longitudinal growth of bones occurs at the growth plates, where chondrocytes align into columns that allow directional growth. Mechanical load and force on chondrocytes regulate the organization of the postnatal growth plate and limb length.

Keywords: loading regulates; growth plate; mechanical loading; growth; organization; postnatal growth

Journal Title: Molecular Biology of the Cell
Year Published: 2017

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