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The caveolin scaffolding domain mediates the promigratory activity of Src-phosphorylated (on Y14) caveolin-1 and, specifically, regulation of vinculin tension in focal adhesions. This suggests that pY14Cav1 enhances cancer cell migration… Click to show full abstract
The caveolin scaffolding domain mediates the promigratory activity of Src-phosphorylated (on Y14) caveolin-1 and, specifically, regulation of vinculin tension in focal adhesions. This suggests that pY14Cav1 enhances cancer cell migration by promoting engagement of focal adhesion traction.
Keywords:
caveolin scaffolding;
scaffolding domain;
caveolin;
focal adhesions;
cancer cell;
cell
Journal Title: Molecular Biology of the Cell
Year Published: 2017
Link to full text (if available)
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Journal Title: Molecular Biology of the Cell
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!