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The nonmotor adaptor protein HMMR maintains the kinetics and integrity of chromosome segregation by promoting TPX2-Eg5 complexes that dampen Eg5-mediated forces and support K-fiber stability, kinetochore–microtubule attachments, and inter-kinetochore tension.… Click to show full abstract
The nonmotor adaptor protein HMMR maintains the kinetics and integrity of chromosome segregation by promoting TPX2-Eg5 complexes that dampen Eg5-mediated forces and support K-fiber stability, kinetochore–microtubule attachments, and inter-kinetochore tension. HMMR is needed to prevent the generation of aneuploid progeny cells.
Keywords:
kinetics integrity;
hmmr;
eg5 mediated;
chromosome segregation;
nonmotor adaptor;
integrity chromosome
Journal Title: Molecular Biology of the Cell
Year Published: 2018
Link to full text (if available)
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Journal Title: Molecular Biology of the Cell
Year Published: 2018
Link to full text (if available)
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recommendations!