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Spontaneous psoas haematoma from enhanced venous thromboembolism (VTE) prophylaxis for COVID-19 infection

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An 89-year-old female patient dropped her haemoglobin by over 40 g/l, and hence required blood transfusion whilst being treated for COVID-19 pneumonia. She had no external bleeding and physical examination… Click to show full abstract

An 89-year-old female patient dropped her haemoglobin by over 40 g/l, and hence required blood transfusion whilst being treated for COVID-19 pneumonia. She had no external bleeding and physical examination was unremarkable. Computed tomography imaging revealed that she had a large right-sided psoas haematoma (Figure 1). Sadly, the patient died despite active treatment. All adult patients are required to be assessed for venous thromboembolism (VTE) prophylaxis (NG 89). This patient received an enhanced regime of low-molecular weight heparin (LMWH) as per NICE guidelines (NG 186) due to the increased risk of VTE in COVID-19. [1] Unilateral spontaneous psoas haematomas have previously been described in the use of the standard prophylactic dose of LMWH. [2] These often present with non-specific symptoms, and hence, diagnosis can be difficult. [3] Older patients, often with multiple co-morbidities require tailored treatment plans in the prevention of VTE in COVID-19 due to the risk of internal bleeding. Patients with a fall in haemoglobin and no clinical findings may benefit from radiological investigation to exclude spontaneous internal haemorrhage.

Keywords: vte; psoas haematoma; vte prophylaxis; venous thromboembolism; spontaneous psoas; thromboembolism vte

Journal Title: Age and Ageing
Year Published: 2021

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