LAUSR

Only two-thirds of Americans meet the recommended 7 hours of sleep each night. Insufficient sleep and disruptions in circadian rhythm have been associated with numerous adverse health outcomes, including diabetes and cardiovascular disease. Several environmental disruptors of sleep have been previously reported, such as artificial light at night (ALAN) and noise. These studies tended to evaluate exposures individually. We evaluated the association between several spatially derived environmental exposures (ALAN, noise, greenspace, and air pollution) and self-reported sleep outcomes obtained in 2012-2015 in a large, prospective cohort of 51,562 California women in the California Teachers Study cohort. Odds ratios (OR) and 95% confidence intervals (95% CI) were calculated for sleep duration and sleep latency. After adjusting for age, race/ethnicity, chronotype, use of sleep medication, and self-reported trouble sleeping, ALAN (OR per 5 mcd/m2 brightness: 1.13, 95% CI 1.07-1.20) and air pollution (OR per 5 ug/m3 PM2.5: 1.06, 95% CI 1.04-1.09) were associated with shorter sleep duration (<7 hours), and noise was associated with longer sleep latency (>15 minutes) (OR per 10 dB: 1.05, 95% CI 1.01-1.10). Greenspace was associated with increased sleep duration (OR per 0.1 units: 0.41, 95% CI 0.28-0.60) and decreased sleep latency (OR per 0.1 units: 0.55, 95% CI 0.39-0.78). Further research is necessary to understand how these and other exposures (e.g., diet) perturb an individuals' inherited sleep patterns and contribute to downstream health outcomes.