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Case 1: A 76-year-old woman who had no smoking history presented with left eyelid ptosis and grade 4 creatine phosphokinase elevation after the 2nd cycle of nivolumab monotherapy. She was… Click to show full abstract
Case 1: A 76-year-old woman who had no smoking history presented with left eyelid ptosis and grade 4 creatine phosphokinase elevation after the 2nd cycle of nivolumab monotherapy. She was diagnosed with lung adenocarcinoma which had EGFR mutation. Dyspnea and muscle weakness developed rapidly with an acute exacerbation. We diagnosed her with myasthenia gravis based on the symptoms and the detection of anti-acetylcholine receptor antibody. She was received plasmapheresis and intravenous immune globulin followed by low dose prednisolone. Her symptoms gradually improved.
Journal Title: Annals of Oncology
Year Published: 2017
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