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Bali-Phy version 3: model-based co-estimation of alignment and phylogeny

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SUMMARY We describe improvements to BAli-Phy, a Markov chain Monte Carlo (MCMC) program that jointly estimates phylogeny, alignment, and other parameters from unaligned sequence data. Version 3 is substantially faster… Click to show full abstract

SUMMARY We describe improvements to BAli-Phy, a Markov chain Monte Carlo (MCMC) program that jointly estimates phylogeny, alignment, and other parameters from unaligned sequence data. Version 3 is substantially faster for large trees, and implements covarion models, additional codon models, and other new models. It implements ancestral state reconstruction, allows prior selection for all model parameters, and can also analyze multiple genes simultaneously. AVAILABILITY Software is available for download at http://www.bali-phy.org. C++ source code is freely available on Github under the GPL2 License.

Keywords: phy version; bali phy; phy; alignment; model

Journal Title: Bioinformatics
Year Published: 2021

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