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RCSB Protein Data Bank 1D3D module: displaying positional features on macromolecular assemblies

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Abstract Motivation Mapping positional features from one-dimensional (1D) sequences onto three-dimensional (3D) structures of biological macromolecules is a powerful tool to show geometric patterns of biochemical annotations and provide a… Click to show full abstract

Abstract Motivation Mapping positional features from one-dimensional (1D) sequences onto three-dimensional (3D) structures of biological macromolecules is a powerful tool to show geometric patterns of biochemical annotations and provide a better understanding of the mechanisms underpinning protein and nucleic acid function at the atomic level. Results We present a new library designed to display fully customizable interactive views between 1D positional features of protein and/or nucleic acid sequences and their 3D structures as isolated chains or components of macromolecular assemblies. Availability and implementation https://github.com/rcsb/rcsb-saguaro-3d. Supplementary information Supplementary data are available at Bioinformatics online.

Keywords: rcsb protein; macromolecular assemblies; data bank; positional features; bank 1d3d; protein data

Journal Title: Bioinformatics
Year Published: 2022

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