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Grenepipe: a Flexible, Scalable and Reproducible Pipeline to Automate Variant Calling from Sequence Reads

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SUMMARY We developed grenepipe, an all-in-one Snakemake workflow to streamline the data processing from raw high-throughput sequencing data of individuals or populations to genotype variant calls. Our pipeline offers a… Click to show full abstract

SUMMARY We developed grenepipe, an all-in-one Snakemake workflow to streamline the data processing from raw high-throughput sequencing data of individuals or populations to genotype variant calls. Our pipeline offers a range of popular software tools within a single configuration file, automatically installs software dependencies, is highly optimized for scalability in cluster environments, and runs with a single command. AVAILABILITY grenepipe is published under the GPLv3, and freely available at github.com/moiexpositoalonsolab/grenepipe.

Keywords: scalable reproducible; grenepipe flexible; reproducible pipeline; pipeline automate; pipeline; flexible scalable

Journal Title: Bioinformatics
Year Published: 2022

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