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The TMCrys server for supporting crystallization of transmembrane proteins

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Abstract Motivation Due to their special properties, the structures of transmembrane proteins are extremely hard to determine. Several methods exist to predict the propensity of successful completion of the structure… Click to show full abstract

Abstract Motivation Due to their special properties, the structures of transmembrane proteins are extremely hard to determine. Several methods exist to predict the propensity of successful completion of the structure determination process. However, available predictors incorporate data of any kind of proteins, hence they can hardly differentiate between crystallizable and non-crystallizable membrane proteins. Results We implemented a web server to simplify running TMCrys prediction method that was developed specifically to separate crystallizable and non-crystallizable membrane proteins. Availability and implementation http://tmcrys.enzim.ttk.mta.hu Supplementary information Supplementary data are available at Bioinformatics online.

Keywords: crystallization transmembrane; transmembrane proteins; tmcrys server; server supporting; supporting crystallization

Journal Title: Bioinformatics
Year Published: 2019

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