Photo by impulsq from unsplash
Gerstmann-Sträussler-Scheinker disease (GSS) is characterized by atypical N- and C-terminal cleaved protease-resistant PrPSc. Vanni et al. report that PrPSc oligomers purified from patients with GSS are authentic – but non-fibrillar… Click to show full abstract
Gerstmann-Sträussler-Scheinker disease (GSS) is characterized by atypical N- and C-terminal cleaved protease-resistant PrPSc. Vanni et al. report that PrPSc oligomers purified from patients with GSS are authentic – but non-fibrillar – prions, thus uncovering the minimal prion protein domain able to encode infectious prions.
Keywords:
isolation infectious;
prion;
non fibrillar;
disease;
infectious non
Journal Title: Brain
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: Brain
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!