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Fuentes-Fayos et al. show that the expression of spliceosome components and splicing factors is dysregulated in high-grade astrocytomas and glioblastomas. The splicing machinery could be a new source of diagnostic… Click to show full abstract
Fuentes-Fayos et al. show that the expression of spliceosome components and splicing factors is dysregulated in high-grade astrocytomas and glioblastomas. The splicing machinery could be a new source of diagnostic and prognostic biomarkers as well as therapeutic targets, with SRSF3 being a key splicing factor in glioblastomas.
Keywords:
splicing machinery;
machinery;
drives glioblastoma;
dysregulation drives;
machinery dysregulation;
glioblastoma development
Journal Title: Brain
Year Published: 2020
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Journal Title: Brain
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!