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Autoantibodies linked with voltage-gated potassium channel (VGKC)-complex antibody-mediated limbic encephalitis (LE) bind to hippocampal subfields. Miller et al. report that chronic LGI1 antibody VGKC-complex LE is associated with focal CA3… Click to show full abstract
Autoantibodies linked with voltage-gated potassium channel (VGKC)-complex antibody-mediated limbic encephalitis (LE) bind to hippocampal subfields. Miller et al. report that chronic LGI1 antibody VGKC-complex LE is associated with focal CA3 atrophy on 7.0-Tesla neuroimaging and autobiographical episodic amnesia. The results point to antibody-mediated pathogenicity and CA3-mediated impairment of episodic memory.
Keywords:
complex antibody;
antibody;
ca3;
vgkc complex;
limbic encephalitis
Journal Title: Brain
Year Published: 2017
Link to full text (if available)
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Journal Title: Brain
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!