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In vivo cholinergic basal forebrain atrophy predicts cognitive decline in de novo Parkinson’s disease

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See Gratwicke and Foltynie (doi:10.1093/brain/awx333) for a scientific commentary on this article. Cognitive impairments in Parkinson’s disease show variable onset, severity and progression. Ray et al. demonstrate that the future… Click to show full abstract

See Gratwicke and Foltynie (doi:10.1093/brain/awx333) for a scientific commentary on this article. Cognitive impairments in Parkinson’s disease show variable onset, severity and progression. Ray et al. demonstrate that the future cognitive status of newly diagnosed patients can be predicted from the volume of the nucleus basalis of Meynert, with implications for the development of interventions for cognitive decline in Parkinson’s disease dementia.

Keywords: disease; vivo cholinergic; parkinson disease; cognitive decline; cholinergic basal

Journal Title: Brain
Year Published: 2018

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