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Acute ketamine dysregulates task-related gamma-band oscillations in thalamo-cortical circuits in schizophrenia

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NMDA receptor deficits have been implicated in schizophrenia. Grent-’t-Jong et al. show that treating healthy controls with ketamine triggers changes in neural oscillations during visual processing distinct from those seen… Click to show full abstract

NMDA receptor deficits have been implicated in schizophrenia. Grent-’t-Jong et al. show that treating healthy controls with ketamine triggers changes in neural oscillations during visual processing distinct from those seen in patients with schizophrenia. This suggests that acute NMDA receptor hypofunction does not account for visuo-perceptual deficits in the disorder.

Keywords: dysregulates task; acute ketamine; gamma band; ketamine dysregulates; task related; related gamma

Journal Title: Brain
Year Published: 2018

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