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Using cell culture and animal models of prion diseases, Ishibashi et al. show that type I interferon signalling interferes with prion infection in mammals. A selective type I interferon receptor… Click to show full abstract
Using cell culture and animal models of prion diseases, Ishibashi et al. show that type I interferon signalling interferes with prion infection in mammals. A selective type I interferon receptor agonist inhibits prion invasion and prolongs survival of prion-infected mice, suggesting potential clinical applications.
Keywords:
type interferon;
prion;
interferon protects;
interferon;
protects neurons;
neurons prions
Journal Title: Brain
Year Published: 2019
Link to full text (if available)
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Journal Title: Brain
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!