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Phase 3 randomized, placebo-controlled, double-blind study of lasmiditan for acute treatment of migraine

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Lasmiditan is a selective 5-HT1F receptor agonist without vasoconstrictive activity. In this phase 3 double-blind placebo-controlled study, Goadsby et al. show that lasmiditan is efficacious and relatively well tolerated in… Click to show full abstract

Lasmiditan is a selective 5-HT1F receptor agonist without vasoconstrictive activity. In this phase 3 double-blind placebo-controlled study, Goadsby et al. show that lasmiditan is efficacious and relatively well tolerated in the acute treatment of migraine in adults, including those with cardiovascular risk factors or a prior history of cardiovascular events.

Keywords: phase; treatment migraine; placebo controlled; acute treatment; double blind

Journal Title: Brain
Year Published: 2019

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