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Subependymal giant cell astrocytomas (SEGAs) cause serious neurological complications in patients with tuberous sclerosis complex. Using high-throughput sequencing, Bongaarts et al. identify MAPK/ERK activation in SEGAs, potentially via the "Ragulator… Click to show full abstract
Subependymal giant cell astrocytomas (SEGAs) cause serious neurological complications in patients with tuberous sclerosis complex. Using high-throughput sequencing, Bongaarts et al. identify MAPK/ERK activation in SEGAs, potentially via the "Ragulator complex", and propose that the MAPK/ERK pathway could be a novel treatment target.
Keywords:
cell astrocytomas;
giant cell;
coding non;
subependymal giant
Journal Title: Brain
Year Published: 2019
Link to full text (if available)
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Journal Title: Brain
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!