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APOBEC3A/B deletion polymorphism and cancer risk

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The germline ‘APOBEC3A/B’ deletion polymorphism, previously linked to APOBEC-dependent mutational signatures, was found associated with lung cancer risk among young individuals and age at diagnosis for lung and prostate cancer.… Click to show full abstract

The germline ‘APOBEC3A/B’ deletion polymorphism, previously linked to APOBEC-dependent mutational signatures, was found associated with lung cancer risk among young individuals and age at diagnosis for lung and prostate cancer. No associations were found to breast or colon cancer.

Keywords: cancer; cancer risk; deletion polymorphism; apobec3a deletion

Journal Title: Carcinogenesis
Year Published: 2018

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