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LARP4B gene mutation is involved in the development of neurofibroma.

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In previous studies, the protein La-related protein 4B (LARP4B) has not been linked to neurofibroma. The gene sequencing results of our patient suggest that LARP4B may play a role in… Click to show full abstract

In previous studies, the protein La-related protein 4B (LARP4B) has not been linked to neurofibroma. The gene sequencing results of our patient suggest that LARP4B may play a role in the growth of neurofibroma without the NF1 gene mutation, making the tumour size larger than that of normal neurofibroma. Exploring the role of LARP4B in the growth process of neurofibroma may help provide a new solution for clinical treatment of this tumour.

Keywords: gene mutation; larp4b gene; gene; mutation involved; neurofibroma

Journal Title: Clinical and experimental dermatology
Year Published: 2022

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