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Acne vulgaris: navigating the NICE recommendations for specialist referral, patient expectations, and the isotretinoin product licence.

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Oral isotretinoin is a highly effective drug for severe acne but with ongoing serious safety concerns, and we are cautiously reminded by the Medicines and Healthcare products Regulatory Authority (MHRA)… Click to show full abstract

Oral isotretinoin is a highly effective drug for severe acne but with ongoing serious safety concerns, and we are cautiously reminded by the Medicines and Healthcare products Regulatory Authority (MHRA) to prescribe this drug within licence. We review the National Institute for Health and Care Excellence (NICE) recommendations for considering referral of acne to specialist care and propose some improvements. This may help manage patient expectations of treatment, ensure only appropriate cases are seen in secondary care, and help prescribers remain within the isotretinoin product licence.

Keywords: licence; product licence; nice recommendations; patient expectations; isotretinoin product

Journal Title: Clinical and experimental dermatology
Year Published: 2023

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