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Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis

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Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients… Click to show full abstract

Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving adjunctive corticosteroids had a significant reduction in secondary cerebrovascular events (P = .0049). Those with CM-associated cerebrovascular events (8%) may benefit from short-term corticosteroids.

Keywords: adjunctive corticosteroid; coccidioidal; therapy treatment; corticosteroid therapy; coccidioidal meningitis

Journal Title: Clinical Infectious Diseases
Year Published: 2017

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