LAUSR

SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila Alessandra Zanon1,†, Sreehari Kalvakuri2,†, Aleksandar Rakovic3,†, Luisa Foco1, Marianna Guida1, Christine Schwienbacher1, Alice Serafin1, Franziska Rudolph3, Michaela Trilck3, Anne Grünewald3,4, Nancy Stanslowsky5, Florian Wegner5, Valentina Giorgio6, Alexandros A. Lavdas1, Rolf Bodmer2, Peter P. Pramstaller1,7,8, Christine Klein3,*, Andrew A. Hicks1,*, Irene Pichler1,† and Seibler Philip3,† 1Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, 39100 Bolzano, Italy, 2Development, Aging and Regeneration Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA, 3Institute of Neurogenetics, University of Lübeck, 23562 Lübeck, Germany, 4Molecular and Functional Neurobiology Group, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4367 Belvaux, Luxembourg, 5Department of Neurology, Hannover Medical School, 30625 Hannover, Germany, 6University of Padova, 35122 Padova, Italy, 7Department of Neurology, General Central Hospital, 39100 Bolzano, Italy and 8Department of Neurology, University of Lübeck, 23562 Lübeck, Germany