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in GenBank. The sequence of Tn7407, including the alternative integration site, matched closely the sequence of a bovine P. multocida isolated in 2013 in the USA (GenBank accession no. CP015567)… Click to show full abstract
in GenBank. The sequence of Tn7407, including the alternative integration site, matched closely the sequence of a bovine P. multocida isolated in 2013 in the USA (GenBank accession no. CP015567) (Figure 1b). This finding underlined the wide distribution of highly similar ICEs with variable resistance regions among epidemiologically unrelated P. multocida from cattle. The results of the study showed the occurrence of MDR P. multocida and M. haemolytica isolates carrying unusual resistance geneswithinmultiresistance-mediating ICEs, which have so far not been described in Europe. These elements might enhance the spread of resistance genes among the respective pathogens and diminish treatment options for BRD in the future.
Journal Title: Journal of Antimicrobial Chemotherapy
Year Published: 2022
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