The PRAME gene plays an important role on reproduction function in cattle and that gene almost present in high copy number in the mammalian genome. Copy number variation (CNV) states… Click to show full abstract
The PRAME gene plays an important role on reproduction function in cattle and that gene almost present in high copy number in the mammalian genome. Copy number variation (CNV) states have been used in population genetics studies to identify population divergences due to alterations in copy number regions or genes and to identify their impact on economic interest traits, including reproductive traits. The aim of this study was to identify the copy number differences of the PRAME gene within the Gir, Holstein, and Girolando breeds. We analyzed two whole genome sequencing datasets from Girolando bulls, 13 from Gir and five from Holstein. A read depth method was performed using the Tatiane Seleguim Chud Centre for Genetic Improvement of Livestock, Dept of Animal Biosciences, University of Guelph.
               
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