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Minimal-activity/low-dose PET/CT-a problem-solving tool for uncertain pulmonary PET findings without correlative CT lesions.

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Focal fluorodeoxyglucose (FDG) uptake in the lung without corresponding morphological lesion is a pitfall in PET/CT interpretation and may be caused by FDG microembolism, which is a sporadic finding. An… Click to show full abstract

Focal fluorodeoxyglucose (FDG) uptake in the lung without corresponding morphological lesion is a pitfall in PET/CT interpretation and may be caused by FDG microembolism, which is a sporadic finding. An FDG-marked blood clot arises during intravenous injection of the radiotracer and is subsequently distributed by the bloodstream to a peripheral lung arteriole. Being without clinical relevance, it may lead to false interpretation and therapeutic consequences. Repeated PET/CT scanning has been recommended, which should show resolution of the focus. However, it would cause additional radiation burden, particularly relevant in young patients, and costs. Figure 1.

Keywords: pet; low dose; dose pet; activity low; pet problem; minimal activity

Journal Title: Japanese journal of clinical oncology
Year Published: 2017

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