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T cells go with the flow: Aquaporin 4 is required for full T cell activation.

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Proximal T-cell receptor signaling and subsequent T cell activation was reduced downstream of anti-CD3/CD28 ligation through small molecule inhibition of the water channel aquaporin 4. Click to show full abstract

Proximal T-cell receptor signaling and subsequent T cell activation was reduced downstream of anti-CD3/CD28 ligation through small molecule inhibition of the water channel aquaporin 4.

Keywords: flow aquaporin; cell; aquaporin required; cell activation; cells flow

Journal Title: Journal of leukocyte biology
Year Published: 2023

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