LAUSR

Abstract Objectives This study examined the extent to which the severity of andropause symptoms affects daily functioning, specifically in work, housework, outings, social relationships, and leisure activities, among employed Japanese men. Methods A cross-sectional internet-based survey was conducted in September 2024. Participants (n = 1054), aged 20-69 years, completed the Aging Males’ Symptoms scale to evaluate symptom severity. Impacts on daily life were assessed using a 4-point scale. Multivariate logistic regression analyses estimated odds ratios (ORs) and 95% CIs. Results After adjusting for relevant covariates, moderate and severe symptoms were significantly associated with greater difficulties in daily life. Compared with individuals with very mild symptoms, those with moderate symptoms had higher ORs for severe difficulties in work (OR = 7.2; 95% CI, 2.9-18.0), social relationships (OR = 17.7; 95% CI, 4.0-78.4), and housework (OR = 3.2; 95% CI, 1.2-9.0). Associations were stronger for severe symptoms: work (OR = 21.1; 95% CI, 8.0-55.5), social relationships (OR = 37.2; 95% CI, 7.9-174.3), and housework (OR = 8.5; 95% CI, 2.9-24.4). Severe symptoms were also linked to significant difficulties in outings (OR = 4.7; 95% CI, 1.8-12.4) and leisure (OR = 8.2; 95% CI, 3.0-22.5). Conclusions Andropause symptoms significantly affect multiple areas of daily life, particularly work, social engagement, and household tasks. These findings underscore the importance of early recognition and intervention.