Paradoxical reactions in central nervous system tuberculosis (CNS-TB) are associated with significant morbidity and mortality. We describe 4 HIV-uninfected children treated for CNS-TB with severe paradoxical reactions unresponsive to corticosteroids.… Click to show full abstract
Paradoxical reactions in central nervous system tuberculosis (CNS-TB) are associated with significant morbidity and mortality. We describe 4 HIV-uninfected children treated for CNS-TB with severe paradoxical reactions unresponsive to corticosteroids. All made recovery after treatment with infliximab, highlighting the safety and effectiveness of infliximab for this complication, and need for prospective trials.
Keywords:
nervous system;
central nervous;
paradoxical reactions;
system tuberculosis
Journal Title: Journal of the Pediatric Infectious Diseases Society
Year Published: 2021
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Journal Title: Journal of the Pediatric Infectious Diseases Society
Year Published: 2021
Link to full text (if available)
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recommendations!