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Breadth and Dynamics of Human Norovirus-Specific Antibodies in the First Year of Life

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Abstract We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months… Click to show full abstract

Abstract We measured antibody binding to diverse norovirus virus-like particles over 12 months in 16 children. All had maternal antibodies at 2 months, with estimated lowest levels at 5 months of age. Antibody increases after 3 months suggested natural infections. This information could guide the timing of future norovirus vaccines.

Keywords: dynamics human; antibodies first; specific antibodies; breadth dynamics; norovirus specific; human norovirus

Journal Title: Journal of the Pediatric Infectious Diseases Society
Year Published: 2022

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