We performed an observational cohort study to assess associations between genetic factors of dengue fever (DF) severity in children in the Dominican Republic. 488 participants had serologically confirmed DF. We… Click to show full abstract
We performed an observational cohort study to assess associations between genetic factors of dengue fever (DF) severity in children in the Dominican Republic. 488 participants had serologically confirmed DF. We replicated the association between IFIH1 gene (rs1990760) and severe DF (n=80/488, p=0.006) and identified novel associations needing further investigation.
               
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