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We compared the clinical course of neonates with persistence of herpes simplex virus (HSV) deoxyribonucleic acid (DNA) in the cerebrospinal fluid (CSF) after 21 days of treatment with high-dose acyclovir… Click to show full abstract
We compared the clinical course of neonates with persistence of herpes simplex virus (HSV) deoxyribonucleic acid (DNA) in the cerebrospinal fluid (CSF) after 21 days of treatment with high-dose acyclovir to that of neonates with clearance of the CSF after 21 days of therapy. Neonates with persistence of HSV DNA had a more severe clinical course with worse neurodevelopmental outcomes.
Keywords:
simplex virus;
deoxyribonucleic acid;
cerebrospinal fluid;
herpes simplex
Journal Title: Journal of the Pediatric Infectious Diseases Society
Year Published: 2018
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Journal Title: Journal of the Pediatric Infectious Diseases Society
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!