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Four genomic clades of Candida auris identified in Canada, 2012-2019.

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Candida auris is an emerging yeast that is associated with antifungal resistance and healthcare-associated outbreaks. From 2012-2019, there were 24 known cases of C. auris colonization or infection in Canada.… Click to show full abstract

Candida auris is an emerging yeast that is associated with antifungal resistance and healthcare-associated outbreaks. From 2012-2019, there were 24 known cases of C. auris colonization or infection in Canada. Isolates were from axilla/groin (n = 6), ear (n = 5), blood (n = 4), toe (n = 2), and a variety of other sites (n = 7). Canadian isolates belonged to the four main genomic clades: Clade I (formerly called South Asian clade, n = 12), Clade II (East Asian, n = 3), Clade III (African, n = 4), and Clade IV (South American, n = 5).  Isolates within each clade were clonal, however, whole genome sequencing may be helpful in identifying clusters within healthcare facilities.

Keywords: clades candida; canada; genomic clades; four genomic; candida auris; 2012 2019

Journal Title: Medical mycology
Year Published: 2021

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