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BACKGROUND In the current study, we aimed to investigate the effect of smoking on inadequate response to Methotrexate (MTX-IR) in rheumatoid arthritis (RA) patients. METHODS We searched PubMed, Embase, and… Click to show full abstract
BACKGROUND In the current study, we aimed to investigate the effect of smoking on inadequate response to Methotrexate (MTX-IR) in rheumatoid arthritis (RA) patients. METHODS We searched PubMed, Embase, and Web of Science until 6 June 2022. Observational or interventional studies investigating MTX-IR in RA patients based on smoking status were included. Two independent reviewers assessed the risk of bias and the certainty of the evidence using ROBINS-I and grades of recommendation, assessment, development, and evaluation (GRADE) tools, respectively.
Journal Title: Modern rheumatology
Year Published: 2023
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