LAUSR

2.11 6 0.017, p = 0.023) and lower average values of pH (7.29 6 0.02 vs 7.32 6 0.015, p = 0.040) and creatinine (463.97 6 36.24 vs 486.0 6 36.25, p = 0.001) in relation to the NA group. No significant difference was found in relation to invasive mechanical ventilation, vasopressors therapy, SAPS II score, oliguria / anuria, recovery of renal function, the length of hospital stay and mortality (p> 0.05) (Table 1). Compared to treatment parameters, the RCA group had a significantly lower number of procedures (4.33 6 2.80 vs 5.81 6 1.28, p = 0.027) and ultrafiltration rate (2.79 6 0.19 vs 3.14 6 0.33, p = 0.015) and significantly longer hemofilter lifespan compared to NA group (24.64 6 0.48 vs 18.10 6 0.58, p = 0.000). Although the prevalence of bleeding was higher in the NA group, no significant difference was found between the groups (37.5% vs 28.20%, p = 0.498), as well as in the infusion of red blood cell (33.3% vs 37.5%, p = 0.768), fresh frozen plasma (28.2% vs 50%, p = 0.742) and platelets (35.89 vs 31.25, p = 0.123). The overall citrate accumulation (CA> 2.25) rate was 5.12% in the RCA group (Table 2). The Kaplan-Meier survival analysis using the log-rank test (Mantel-Cox test) for comparing the hemofilter lifespan between RCA and NA regime found a significant difference in survival between the groups (v2 = 3,789, p = 0,049) (Figure 1). Multiple regression model for testing risk factors SAPS II score, Oxiris membrane, UF, lactate, hemoglobin concentration, platelet count, Activated Partial Thromboplastin Time and Prothrombin Time on hemofilter survival has shown a significant linear relationship without statistical significance in both RCA groups (R=0.544 ; F=1.575) and NA (R=0.757; F=1.171) (Table 3).