LAUSR

To the Editor: We performed a literature review on viral epidemics and pandemics, including the severe acute respiratory syndrome (SARS), the Middle East respiratory syndrome (MERS), influenza H1N1, and the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with the goal of identifying the neurological symptoms, signs, and complications of these infections within the context of the COVID-19 pandemic (Figure). Of 16 articles that included 8042 patients with H1N1, neurological involvement was reported in 1286 patients (15.99%). Excluding headaches, 771 patients had neurological involvement (9.6%) (Table 1). Of 8 articles consisting of 1128 patients with MERS, 323 patients (28.6%) had neurological findings and 170 patients (15.07%) without headache. Of 5 articles with 1251 patients with SARS, 187 patients (14.95%) were reported to have neurological involvement and 6.2% (n = 78) with the exclusion of headache. Of 17 articles on 5335 patients with COVID-19, 744 patients were reported to have neurological signs, symptoms,