LAUSR

Abstract Please see the full‐text version of this guideline (https://www.cns.org/guidelines/guidelines‐management‐patients‐vestibular‐schwannoma/chapter_3) for the target population of each recommendation listed below. STEREOTACTIC RADIOSURGERY Question 1: What is the overall probability of maintaining serviceable hearing following stereotactic radiosurgery utilizing modern dose planning, at 2, 5, and 10 yr following treatment? Recommendation: Level 3: Individuals who meet these criteria and are considering stereotactic radiosurgery should be counseled that there is moderately high probability (>50%‐75%) of hearing preservation at 2 yr, moderately high probability (>50%‐75%) of hearing preservation at 5 yr, and moderately low probability (>25%‐50%) of hearing preservation at 10 yr. Question 2: Among patients with AAO‐HNS (American Academy of Otolaryngology‐Head and Neck Surgery hearing classification) class A or GR (Gardner‐Robertson hearing classification) grade I hearing at baseline, what is the overall probability of maintaining serviceable hearing following stereotactic radiosurgery, utilizing modern dose planning, at 2, 5, and 10 yr following treatment? Recommendation: Level 3: Individuals who meet these criteria and are considering stereotactic radiosurgery should be counseled that there is a high probability (>75%‐100%) of hearing preservation at 2 yr, moderately high probability (>50%‐75%) of hearing preservation at 5 yr, and moderately low probability (>25%‐50%) of hearing preservation at 10 yr. Question 3: What patient‐ and tumor‐related factors influence progression to nonserviceable hearing following stereotactic radiosurgery using ≤13 Gy to the tumor margin? Recommendation: Level 3: Individuals who meet these criteria and are considering stereotactic radiosurgery should be counseled regarding the probability of successful hearing preservation based on the following prognostic data: the most consistent prognostic features associated with maintenance of serviceable hearing are good preoperative word recognition and/or pure tone thresholds with variable cut‐points reported, smaller tumor size, marginal tumor dose ≤12 Gy, and cochlear dose ≤4 Gy. Age and sex are not strong predictors of hearing preservation outcome. MICROSURGERY Question 4 What is the overall probability of maintaining serviceable hearing following microsurgical resection of small to medium‐sized sporadic vestibular schwannomas early after surgery, at 2, 5, and 10 yr following treatment? Recommendation Level 3: Individuals who meet these criteria and are considering microsurgical resection should be counseled that there is a moderately low probability (>25%‐50%) of hearing preservation immediately following surgery, moderately low probability (>25%‐50%) of hearing preservation at 2 yr, moderately low probability (>25%‐50%) of hearing preservation at 5 yr, and moderately low probability (>25%‐50%) of hearing preservation at 10 yr. Question 5 Among patients with AAO‐HNS class A or GR grade I hearing at baseline, what is the overall probability of maintaining serviceable hearing following microsurgical resection of small to medium‐sized sporadic vestibular schwannomas early after surgery, at 2, 5, and 10 yr following treatment? Recommendation Level 3: Individuals who meet these criteria and are considering microsurgical resection should be counseled that there is a moderately high probability (>50%‐75%) of hearing preservation immediately following surgery, moderately high probability (>50%‐75%) of hearing preservation at 2 yr, moderately high probability (>50%‐75%) of hearing preservation at 5 yr, and moderately low probability (>25%‐50%) of hearing preservation at 10 yr. Question 6 What patient‐ and tumor‐related factors influence progression to nonserviceable hearing following microsurgical resection of small to medium‐sized sporadic vestibular schwannomas? Recommendation Level 3: Individuals who meet these criteria and are considering microsurgical resection should be counseled regarding the probability of successful hearing preservation based on the following prognostic data: the most consistent prognostic features associated with maintenance of serviceable hearing are good preoperative word recognition and/or pure tone thresholds with variable cut‐points reported, smaller tumor size commonly less than 1 cm, and presence of a distal internal auditory canal cerebrospinal fluid fundal cap. Age and sex are not strong predictors of hearing preservation outcome. CONSERVATIVE OBSERVATION Question 7 What is the overall probability of maintaining serviceable hearing with conservative observation of vestibular schwannomas at 2, 5, and 10 yr following diagnosis? Recommendation Level 3: Individuals who meet these criteria and are considering observation should be counseled that there is a high probability (>75%‐100%) of hearing preservation at 2 yr, moderately high probability (>50%‐75%) of hearing preservation at 5 yr, and moderately low probability (>25%‐50%) of hearing preservation at 10 yr. Question 8 Among patients with AAO‐HNS class A or GR grade I hearing at baseline, what is the overall probability of maintaining serviceable hearing with conservative observation at 2 and 5 yr following diagnosis? Recommendation Level 3: Individuals who meet these criteria and are considering stereotactic radiosurgery should be counseled that there is a high probability (>75%‐100%) of hearing preservation at 2 yr, and moderately high probability (>50%‐75%) of hearing preservation at 5 yr. Insufficient data were available to determine the probability of hearing preservation at 10 yr for this population subset. Question 9 What patient and tumor‐related factors influence progression to nonserviceable hearing during conservative observation? Recommendation Level 3: Individuals who meet these criteria and are considering observation should be counseled regarding probability of successful hearing preservation based on the following prognostic data: the most consistent prognostic features associated with maintenance of serviceable hearing are good preoperative word recognition and/or pure tone thresholds with variable cut‐points reported, as well as nongrowth of the tumor. Tumor size at the time of diagnosis, age, and sex do not predict future development of nonserviceable hearing during observation. The full guideline can be found at: https://www.cns.org/guidelines/guidelines‐manage‐ment‐patients‐vestibular‐schwannoma/chapter_3.