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Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation

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Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation Feng-Liang Liu1,†, Kaixin Wu2,3,7,8,†, Jiaoyang Sun3,4,6,†, Zilei Duan1,†, Xiongzhi Quan2,3, Junqi Kuang2,3,4, Shilong Chu2,3, Wei Pang2,3, Han… Click to show full abstract

Rapid generation of ACE2 humanized inbred mouse model for COVID-19 with tetraploid complementation Feng-Liang Liu1,†, Kaixin Wu2,3,7,8,†, Jiaoyang Sun3,4,6,†, Zilei Duan1,†, Xiongzhi Quan2,3, Junqi Kuang2,3,4, Shilong Chu2,3, Wei Pang2,3, Han Gao2, Ling Xu1, Ying-Chang Li1, Hai-Lin Zhang1, Xue-Hui Wang1, Rong-Hua Luo1, Xiao-Li Feng5, Hans R. Schöler9,10, Xinwen Chen3,4, Duanqing Pei2, Guangming Wu2,∗, Yong-Tang Zheng1,2,5,∗ and Jiekai Chen2,3,6,∗

Keywords: ace2 humanized; generation ace2; inbred mouse; humanized inbred; mouse model; rapid generation

Journal Title: National Science Review
Year Published: 2021

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