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False Rifampicin Resistance in Xpert Ultra Applied to Lymph Node Aspirate: A Case Report

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Abstract A 36-year-old male patient was diagnosed with tuberculosis in Antwerp, Belgium, in May 2018. His lymph node aspirate initially tested rifampicin resistant in Xpert MTB/RIF Ultra, but tested susceptible… Click to show full abstract

Abstract A 36-year-old male patient was diagnosed with tuberculosis in Antwerp, Belgium, in May 2018. His lymph node aspirate initially tested rifampicin resistant in Xpert MTB/RIF Ultra, but tested susceptible in all other tests including targeted deep sequencing due to a rare matrix effect in the Xpert MTB/RIF Ultra reaction tube.

Keywords: resistance xpert; node aspirate; false rifampicin; xpert; lymph node; rifampicin resistance

Journal Title: Open Forum Infectious Diseases
Year Published: 2020

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