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Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection

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Abstract Cytomegalovirus (CMV) increases tuberculosis (TB) risk, but its relationship with latent TB infection (LTBI) is unknown. Using US nationally representative data, we report that CMV was independently associated with… Click to show full abstract

Abstract Cytomegalovirus (CMV) increases tuberculosis (TB) risk, but its relationship with latent TB infection (LTBI) is unknown. Using US nationally representative data, we report that CMV was independently associated with LTBI (odds ratio, 2.94; 95% CI, 1.19–7.28; P=.02). CMV and LTBI were associated with higher C-reactive protein, suggesting chronic inflammation.

Keywords: cytomegalovirus infection; associated increased; tuberculosis; infection; increased prevalence; infection associated

Journal Title: Open Forum Infectious Diseases
Year Published: 2021

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