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Dolutegravir Resistance in Malawi’s National HIV Treatment Program

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Abstract Dolutegravir HIV drug resistance (HIVDR) data from Africa remain sparse. We reviewed HIVDR results of Malawians on dolutegravir-based antiretroviral therapy (November 2020–September 2021). Of 6462 eligible clients, 33 samples… Click to show full abstract

Abstract Dolutegravir HIV drug resistance (HIVDR) data from Africa remain sparse. We reviewed HIVDR results of Malawians on dolutegravir-based antiretroviral therapy (November 2020–September 2021). Of 6462 eligible clients, 33 samples were submitted to South Africa, 27 were sequenced successfully, and 8 (30%) had dolutegravir HIVDR. Malawi urgently requires adequate HIVDR testing capacity.

Keywords: resistance malawi; dolutegravir resistance; malawi national; national hiv; resistance; hiv treatment

Journal Title: Open Forum Infectious Diseases
Year Published: 2022

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