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Tecovirimat for the Treatment of Human Monkeypox: An Initial Series From Massachusetts, United States

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Abstract A large, ongoing multicountry outbreak of human monkeypox has the potential to cause considerable morbidity and mortality. Therapeutics for the treatment of smallpox, a related Orthopoxvirus, may be used… Click to show full abstract

Abstract A large, ongoing multicountry outbreak of human monkeypox has the potential to cause considerable morbidity and mortality. Therapeutics for the treatment of smallpox, a related Orthopoxvirus, may be used and affect the natural history of monkeypox. We present 3 patients from our hospitals treated with tecovirimat, a pan-Orthopoxvirus inhibitor currently available under an expanded access investigational new drug protocol for monkeypox.

Keywords: human monkeypox; monkeypox initial; tecovirimat treatment; treatment human; initial series; treatment

Journal Title: Open Forum Infectious Diseases
Year Published: 2022

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