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Abstract In this study, abnormal levels of myeloid activation, endothelial damage and innate immune markers were associated with severe COVID-19, while higher levels of metabolic biomarkers (irisin, leptin), demonstrated a… Click to show full abstract
Abstract In this study, abnormal levels of myeloid activation, endothelial damage and innate immune markers were associated with severe COVID-19, while higher levels of metabolic biomarkers (irisin, leptin), demonstrated a protective effect. These data support a model for COVID-19 immunopathogenesis linking robust inflammation and endothelial damage in metabolically-predisposed individuals.
Keywords:
metabolic biomarkers;
damage;
impact innate;
immunity endothelial;
endothelial damage;
innate immunity
Journal Title: Open Forum Infectious Diseases
Year Published: 2022
Link to full text (if available)
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Journal Title: Open Forum Infectious Diseases
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!