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Effect of Blood Culture Contamination on Antibiotic Use in an Institution With Rapid Laboratory Methods and Phone-Based Clinical Follow-up of Blood Culture Results

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Abstract In a multivariate analysis of 30 574 blood culture (BC) results, BC contamination was associated with only a small increase in antibiotic length of therapy compared to no-growth BCs… Click to show full abstract

Abstract In a multivariate analysis of 30 574 blood culture (BC) results, BC contamination was associated with only a small increase in antibiotic length of therapy compared to no-growth BCs (difference, 0.36 days [95% confidence interval, .05–.67]; P = .02). Stewardship processes at our institution appear to be effective in reducing the impact of BC contamination.

Keywords: culture results; contamination; blood culture; blood; institution

Journal Title: Open Forum Infectious Diseases
Year Published: 2022

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