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Bebtelovimab for High-Risk Outpatients With Early COVID-19 in a Large US Health System

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Abstract There are limited data for the clinical efficacy of bebtelovimab in preventing severe coronavirus disease 2019. Among outpatients unable to take nirmatrelvir-ritonavir at a large health system, 10 of… Click to show full abstract

Abstract There are limited data for the clinical efficacy of bebtelovimab in preventing severe coronavirus disease 2019. Among outpatients unable to take nirmatrelvir-ritonavir at a large health system, 10 of 377 (2.7%) patients who received bebtelovimab and 17 of 377 (4.5%) matched untreated patients were hospitalized or died. The 43% observed risk reduction with bebtelovimab was not statistically significant (P = 0.14).

Keywords: risk; bebtelovimab high; large health; health system

Journal Title: Open Forum Infectious Diseases
Year Published: 2022

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