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Effectiveness of A Fourth Dose of COVID-19 mRNA Vaccine in the Elderly Population During the Omicron BA.2 and BA.5 Circulation: A Nationwide Cohort Study in Korea (K-COVE)

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Abstract We estimate the effectiveness of a fourth dose booster of coronavirus disease 2019 mRNA vaccine in individuals aged ≥60 years during Omicron BA.2 and BA.5 circulation in Korea. The… Click to show full abstract

Abstract We estimate the effectiveness of a fourth dose booster of coronavirus disease 2019 mRNA vaccine in individuals aged ≥60 years during Omicron BA.2 and BA.5 circulation in Korea. The effectiveness against critical infection was 67.7% (95% confidence interval, 50.7%–78.8%) at 31–60 days and 62.1% (95% confidence interval, 45.5%–73.7%) at 61–90 days.

Keywords: effectiveness fourth; fourth dose; mrna vaccine; omicron circulation

Journal Title: Open Forum Infectious Diseases
Year Published: 2023

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